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Tuesday 01 July 2003

In vitro susceptibilities of Malassezia species to a new triazole, albaconazole (UR-9825), and other antifungal compounds.

By: Garau M, Pereiro M Jr, del Palacio A.

Antimicrob Agents Chemother 2003 Jul;47(7):2342-4

The in vitro activity of the new triazole albaconazole (UR-9825) in comparison with those of flucytosine, fluconazole, ketoconazole, itraconazole, and voriconazole against 70 strains of Malassezia spp. was determined by a microdilution method using a colorimetric indicator for metabolic activity. Albaconazole showed an in vitro profile similar to those of the different antifungals tested (MIC <or= 0.06 microg/ml for all the strains).

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