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Thursday 01 January 2004

Oral paracoccidioidomycosis or squamous cell carcinoma?

By: Kaminagakura E, Graner E, de Almeida OP, Di Hipolito Junior O, Lopes MA.

Gen Dent 2004 Jan-Feb;52(1):48-50

Paracoccidioidomycosis is a deep, systemic, and progressive mycosis caused by Paracoccidioides brasiliensis. Oral lesions normally are multiples with a mulberry-like appearance. This article reviews an unusual case involving a chronic, solitary, and ulcerated lesion whose clinical aspects were similar to squamous cell carcinoma. Viewed microscopically, the lesion showed pseudoepitheliomatous hyperplasia and non-necrotizing granulomas. The patient was treated with systemic ketoconazole. Over the next 11 years, follow-up examinations were performed but no recurrence was observed.

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