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Friday 01 February 2002

Invitro drug sensitivity of Trichophyton species against griseofulvin and ketoconazole.

By: Dodia S, Bajpai R, Singh BG.

Hindustan Antibiot Bull 2002 Feb-Nov;44(1-4):47-8

The in vitro activity of griseofulvin and ketoconazole was investigated against Trichophyton mentagrophytes (Robin) Blanchard and T. Simii (Pinoy) Stockdale, Mackenzie and Austwick. A gradual decrease in growth was observed with increase in concentration of both antibiotics. Ketoconazole was the more effective antibiotic than griseofulvin as it observed to inhibit > 50% mycelial weight even at a lower concentration of 100 ppm. While griseofulvin was effective to cause > 50% growth inhibition only at higher dosage of 400 ppm.

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